Simparica Trio Chewable Tablets for Dogs
Simparica Trio is an oral medication for the treatment/prevention of fleas, ticks and certain worms (see below) in dogs. It contains the active ingredients sarolaner, moxidectin and pyrantel.
Available as a pack of 3 tablets or 6 tablets
It comes in 6 sizes depending on the size of your dog. Each size is available in packs of 3 or 6 tablets. 1 tablet to be given monthly.
This is a prescription only medication.
Indications for use:
− For the treatment of tick infestations. The veterinary medicinal product has immediate and
persistent tick killing activity for 5 weeks against Ixodes hexagonus, Ixodes ricinus and
Rhipicephalus sanguineus and for 4 weeks against Dermacentor reticulatus;
− For the treatment of flea infestations (Ctenocephalides felis and Ctenocephalides canis). The
veterinary medicinal product has immediate and persistent flea killing activity against new
infestations for 5 weeks;
For the treatment of gastrointestinal roundworm and hookworm infections:
− Toxocara canis immature adults (L5) and adults;
− Ancylostoma caninum L4 larvae, immature adults (L5) and adults;
− Toxascaris leonina adults;
− Uncinaria stenocephala adults.
− For the prevention of heartworm disease (Dirofilaria immitis);
− For the prevention of angiostrongylosis by reducing the level of infection with immature adult
(L5) stages of Angiostrongylus vasorum.
Available in dog sizes:
1.25-2.5kg (3mg Sarolaner)
2.5-5kg (6mg Sarolaner)
5-10kg (12mg Sarolaner)
10-20kg (24mg Sarolaner)
20-40kg (48mg Sarolaner)
40-60kg (72mg Sarolaner)
Ticks and fleas need to start feeding on the host to become exposed to sarolaner; therefore, the
transmission of infectious parasite-borne diseases cannot be excluded.
This veterinary medicinal product is not effective against adult D. immitis. However, accidental
administration to dogs infected with adult heartworms should not pose safety concerns.
Not suitable for use in puppies less than 8 weeks of age and/or dogs less than 1.25 kg
The product was well tolerated in dogs with a deficient multidrug-resistance-protein 1 (MDR1 -/-).
However, in such sensitive breeds (which may include, but not necessarily limited to, Collies and
related breeds), the recommended dose should be strictly observed.
SPC Datasheets for Simparica Trio:
Dogs weighing 2.5-5kg
Dogs weighing >5-10kg
Dogs weighing >10-20kg
Dogs weighing >20-40kg
Dogs weighing >40-60kg
Sold as a pack of 3 chewable tablets or 6 tablets